目的探讨携带神经的腹直肌-腹膜瓣移植修复舌体缺损的可行性。方法研究选用12只Beagle犬,随机分为3组,制备带神经的腹直肌-腹膜瓣修复舌体缺损的动物模型,其中2组(A、B组)行肋间神经与舌下神经吻合,另一组不行神经吻合。左侧为实验侧,右侧为正常对照侧。术后12周应用激发肌电图,检测舌下神经潜伏期、振幅及传导速度,观察腹直肌-腹膜瓣是否重获舌下神经再支配。结果 12只Beagle犬中9只带神经的腹直肌-腹膜瓣修复舌体缺损的动物模型建立成功,1只雄性犬术后第3天因腹疝死亡,2只雌性犬因动脉解剖与雄性犬差异较大,腹壁下动脉与舌动脉管径相差较大,无法吻合。AB组舌下神经传导速度分别恢复至正常侧的40%、30%。结论采用带神经的腹直肌-腹膜瓣移植修复舌体缺损具有可行性,失神经腹直肌-腹膜瓣可重获舌下神经的支配,舌下神经支配功能可部分恢复。 Objective To investigate the feasibility of repairing the defect of tongue with autograft of rectus abdominis flap. METHODS: Twelve Beagle dogs were randomly divided into three groups. Animal models of tongue defect with rectus abdominis flap repaired by nerve were prepared. The intercostal nerve of the two groups (group A, B) was anastomosed with the hypoglossal nerve , Another group is not nerve anastomosis. The left side is the experimental side, the right side is the normal control side. At 12 weeks after operation, EMG was used to detect sublingual nerve latency, amplitude and conduction velocity, and to observe whether rectus sublingualis was recaptured in rectus abdominis flap. Results Nine animal models of rectus abdominis - peritoneal flap repair in 12 Beagle dogs were established successfully. One male dog died of abdominal hernia on the third day after operation. Two female dogs were sacrificed due to arterial anatomy and males Dog differences, abdominal artery and tongue artery diameter difference is large, can not match. The hypoglossal nerve conduction velocity of AB group was restored to 40% and 30% of the normal side respectively. Conclusions It is feasible to repair the tongue defect by using the rectus abdominis flap with nerve transposition. The denervation of the rectus abdominis flap can recover the sublingual nerves and the hypoglossal nerve can partially recover.