论文部分内容阅读
目的验证Stanford B型主动脉夹层形成的条件,探讨血流因素和管壁因素的相关性。方法12只实验动犬随机分为三组,每组4只,分别进行血流因素、管壁因素及血流、管壁双因素的胸主动脉夹层动物模型建立,分别用单因素敏感性分析及双因素敏感性分析血流和管壁的变化与Stanford B型主动脉夹层形成的相关性。结果血压升高及中膜破坏为胸主动脉夹层形成的敏感因素。经统计学处理表明,在胸主动脉夹层形成的综合因素里中膜的病变贡献率最大。结论管壁因素和血流因素都是胸主动脉夹层形成的必需条件。其中管壁因素是基础因素,血流因素是始动因素。
Objective To verify the formation of Stanford type B aortic dissection and explore the relationship between blood flow factors and wall factors. Methods Twelve experimental dogs were randomly divided into three groups (n = 4 in each group). The animals were divided into three groups according to their blood flow factors, wall factors and blood flow, and the wall of the thoracic aortic dissection animal model. Single factor sensitivity analysis And two-factor sensitivity analysis of blood flow and wall changes and Stanford B aortic dissection correlation. Results The increase of blood pressure and destruction of the middle membrane were the sensitive factors for the formation of thoracic aortic dissection. The statistical analysis showed that in the synthesis of thoracic aortic dissection in the largest contribution to the incidence of lesions in the media. Conclusion Both wall and blood flow factors are necessary for the formation of thoracic aortic dissection. The wall factor is the basic factor, and the blood flow factor is the initial factor.