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选择26例头颈部癌患者，对其放疗前、放疗中及放疗后刺激性混合唾液流率、乳铁素、溶菌酶、淀粉酶与白蛋白的含量进行分析，结果显示：唾液流率和淀粉酶含量在放疗开始后即明显下降，并一直维持在较低水平，半年后更低；唾液乳铁素、溶菌酶与白蛋白的含量在放疗早期明显升高，累积量达40Gy时稍有回落，当累积量达60Gy时，又明显升高，半年后基本恢复到治疗前水平。提示：唾液流率和淀粉酶含量的变化是反映放疗期唾液腺功能受损程度的可靠指标，而乳铁质、溶菌酶与白蛋白的变化是与放疗有关的炎症反应的指标。
Twenty-six patients with head and neck cancer were selected and their irritant mixed salivary flow rate, lactoferrin, lysozyme, amylase, and albumin levels before radiotherapy, during radiotherapy, and after radiotherapy were analyzed. The results showed that: Amylase content decreased significantly after radiotherapy started, and remained at a low level. After half a year, the content of amylase was lower. The content of salivary lactoferrin, lysozyme, and albumin increased significantly at the early stage of radiotherapy. When the cumulative amount reached 40 Gy, there was a slight increase. When the cumulative amount reached 60 Gy, it increased significantly, and it basically returned to the pre-treatment level after six months. Tip: Changes in salivary flow rate and amylase content are reliable indicators of the degree of impairment of salivary gland function during radiotherapy, and changes in lactoferrin, lysozyme, and albumin are indicators of inflammation associated with radiotherapy.