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用免疫组化ABC法，检测50例膀胱移行细胞癌61例次活检C－erbB－2表达与病理分级、临床分期和预后之间的关系。结果：8例次（－），14例次（＋），20例次（++），19例次（+++）。C－erbB－2过度表达与病理分级、临床分期、死亡率和复发率之间呈正相关，有显著差异（P＜0．05）。随着病理分缓升高和肿瘤侵犯深度增加，其与复发组和死亡组之间有显著差异（P＜0．05）。结果提示：C－erbB－2的过度表达是检测膀胱癌病人预后的重要因素。
Immunohistochemical ABC method was used to detect the relationship between the expression of C-erbB-2 and the pathological grade, clinical stage and prognosis in 61 cases of bladder transitional cell carcinoma. Results: 8 cases (-), 14 cases (+), 20 cases (++), 19 cases (+++). There was a positive correlation between C-erbB-2 overexpression and pathological grade, clinical stage, mortality and relapse rate (P <0.05). With the gradual increase of pathology and the increase of tumor invasion depth, there was a significant difference between the two groups (P <0.05). The results suggest that overexpression of C-erbB-2 is an important factor in the prognosis of patients with bladder cancer.