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目的对比研究前列地尔与血塞通治疗急性脑梗死的安全性。方法选取我院2013年1月到2014年1月收治的110例急性脑梗死患者,按照登记表的奇偶数将患者随机分为两组。对照组55例,应用血塞通对患者进行治疗;观察组55例,采用前列地尔对患者进行治疗。观察并对比两组患者的治疗效果及安全性。结果观察组患者神经功能缺损评分(7.89±6.40)显著低于对照组(11.15±5.33),差异有统计学意义(P<0.05);观察组患者生活能力评分(1.9±1.3)及睡眠质量(6.37±0.77)显著高于对照组〔(1.4±1.1),(3.22±1.25)〕,差异有统计学意义(P<0.05)。结论前列地尔注射液治疗急性脑梗死患者,可有效改善患者病情,减少并发症的产生,安全性较高,治疗效果显著。
Objective To compare the safety of alprostadil with Xuesaitong in the treatment of acute cerebral infarction. Methods A total of 110 patients with acute cerebral infarction who were admitted to our hospital from January 2013 to January 2014 were selected and randomly divided into two groups according to their parity. In the control group, 55 cases were treated with Xuesaitong; 55 cases in the observation group were treated with prostaglandin. The therapeutic effect and safety of the two groups were observed and compared. Results The score of neurological deficit in observation group (7.89 ± 6.40) was significantly lower than that in control group (11.15 ± 5.33), the difference was statistically significant (P <0.05); the score of test group was 1.9 ± 1.3 and the quality of sleep 6.37 ± 0.77) was significantly higher than that of the control group (1.4 ± 1.1, 3.22 ± 1.25), the difference was statistically significant (P <0.05). Conclusion Alprostadil injection in patients with acute cerebral infarction, can effectively improve the patient’s condition, reduce complications, higher safety, the treatment effect is remarkable.