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为探讨儿童分泌性中耳炎与肿瘤坏死因子及免疫球蛋白的关系 ,采用 EL ISA双抗体夹心法及免疫扩散试验 ,对 30例健康儿童和 37例分泌性中耳炎患儿进行肿瘤坏死因子 (TNF- α)和免疫球蛋白的测定 .结果分泌性中耳炎 TNF- α明显增高 (P<0 .0 1) ,Ig A明显降低 (P<0 .0 1) ,Ig G、Ig M无明显差异 .推测在分泌性中耳炎的发病过程中 ,免疫机制可起重要作用
To investigate the relationship between secretory otitis media in children and tumor necrosis factor and immunoglobulin, ELISA double antibody sandwich method and immunodiffusion test were performed on 30 healthy children and 37 children with secretory otitis media for tumor necrosis factor (TNF-α ) And immunoglobulin.Results TNF-α in secretory otitis media was significantly increased (P <0.01), Ig A was significantly decreased (P <0.01), Ig G, Ig M was not significantly different Secretory otitis media in the pathogenesis, the immune mechanism may play an important role