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本文对16例鞍区生殖细胞瘤的临床和CT资料进行了分析。结果表明,本病好发于儿童及青年,女性多见。临床常表现为尿崩症、视力障碍及丘脑下部-垂体功能紊乱。CT检查可确定肿瘤的部位,反映肿瘤的内部结构,提供恶性肿瘤的诊断依据以及确定脑积水的梗阻部位、发现蝶鞍局限性骨质破坏等。鞍区生殖细胞瘤起源于丘脑下部,如漏斗、视交叉、垂体柄等。肿瘤平扫呈高密度,少数可有多发、散在、小的低密度区;增强CT强化显著,低密度区无强化。肿瘤形态不规则,边界不清楚,沿脑脊液循环种植性转移及沿邻近室管膜浸润生长等,可视为恶性肿瘤征象,后者对本病具有特征性意义。另外,部分病例鞍区与松果体医生殖细胞瘤并存,检查中要注意寻找。
In this paper, 16 cases of saddlery germ cell tumor clinical and CT data were analyzed. The results show that the disease occurs in children and young people, more common in women. Clinical manifestations of diabetes insipidus, visual impairment and hypothalamus - pituitary dysfunction. CT examination can determine the location of the tumor, reflecting the internal structure of the tumor, provide the basis for the diagnosis of malignant tumors and determine the site of obstruction of hydrocephalus and found that the limited sellar bone destruction and so on. Saddle area germ cell tumors originate in the hypothalamus, such as funnel, optic chiasm, pituitary stalk and so on. Tumor showed a high density scan, a few may have multiple, scattered, small low-density areas; enhanced CT significant enhancement, low-density area without strengthening. Irregular tumor morphology, border is not clear, implanted along the cerebrospinal fluid circulation and infiltration along the adjacent ependymal growth and so on, can be regarded as signs of malignant tumors, the latter has a characteristic significance of the disease. In addition, some cases of the saddle area and pineal tumor symplectic cell tumor coexist, check should pay attention to find.