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考虑到有机硅化合物对心血管系统有调节作用,设计合成了4-位苯基上有三甲硅基取代的1,4-二氢吡啶类化合物6个,药理初筛对大鼠有降血压作用。
Taking into account the organic silicon compounds have a regulatory effect on the cardiovascular system, design and synthesis of a 4-phenyl-substituted trimethylsilyl 1,4-dihydropyridine compounds six pharmacological preliminary screening of rats have antihypertensive effect .