先天性疟疾1例

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患儿,陈××,女,11天,发热9天,于1977年11月19日以“发热待查”收住我院。患儿系第二胎足月顺产,于生后第二天起开始发热,最高达39℃,伴哭吵,口唇时而紫绀,时而苍白,肢端发冷,并短阵惊厥。入院头2天曾先后使用青霉素、链霉素,及中药羚羊角与清热中药方等,但发热如故。第3天后发现其发热有一定规律,即每天下午9时许开始发热至次晨热退,热退后出汗,患儿一般情况好转。追问病史得知其母在妊娠五个月时曾患间日疟,因顾虑服抗疟药后致婴儿畸形而未服氯喹。体检:一足月产新生儿,营养中等,五官端正,前后囟无突起,颈软。口唇略干燥。皮肤及粘膜无 Children, Chen × ×, female, 11 days, fever 9 days, on November 19, 1977 to “fever to be checked,” admitted to our hospital. Pediatric second-term fetus full-term follow-up, the day after birth, began to fever, up to 39 ℃, with crying noisy, sometimes cyanotic lips, sometimes pale, extremities cold, and a short-term convulsion. Admitted to the first two days has been the use of penicillin, streptomycin, and traditional Chinese medicine antelope horn and heat Chinese medicine side, but fever as before. After 3 days found that there are certain laws of fever, that is, every day at 9 pm began to fever the next morning heat back, fever back sweating, children generally improve. Asked about the medical history that his mother had suffered from vivax malaria five months of pregnancy, because of fear of taking anti-malarial drugs to the baby deformity without taking chloroquine. Physical examination: a full-term newborns, moderate nutrition, facial features, no protrusion before and after the skull, neck soft. Slightly dry lips. No skin and mucous membranes
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