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本文采用随机、双盲、安慰剂对照试验评价静注硫酸镁治疗中、重度哮喘的效果。 38例对常用β受体兴奋剂喷雾治疗效果不明显的急性中、重度哮喘病人。直肠体温大于38℃,收缩压小于120mmHg,有肾脏病史,咳脓痰,肺部浸润或妊娠者不列入本研究。随机将病人分为治疗组(19例)和安慰剂组(19例),前组静注硫酸镁1.2 g溶解于50ml生理盐水的溶液;后组静注生理盐水50ml,静注时间均为20分钟。静注前和
This randomized, double-blind, placebo-controlled trial evaluated intravenous magnesium sulfate for the treatment of moderate-to-severe asthma. 38 cases of common beta receptor agonist spray treatment is not obvious in acute moderate and severe asthma patients. Rectal temperature was greater than 38 ℃, systolic blood pressure less than 120mmHg, a history of kidney disease, cough purulent sputum, pulmonary infiltration or pregnancy were not included in this study. The patients were randomly divided into treatment group (19 cases) and placebo group (19 cases). The former group was given intravenous injection of 1.2 g magnesium sulfate dissolved in 50 ml of normal saline solution. The latter group received 50 ml normal saline and intravenous injection time was 20 minute. Before and after intravenous injection