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背景和目的 在CT和MRI中见到单个椭圆形直径大于5mm位于壳核外下方的低密度区[壳核下腔隙(IPLs)],通常报告为腔隙性脑梗塞。为了确定IPLs的临床表现及其病理学改变,我们对I-PLs患者的影像学、临床表现、血管病高危因素及其组织病理学特征进行评估。 方法 连续查阅IPLs的MRI扫描,临床考虑为IPLs的患者也包括在内。用调查表获得患者是否有血管病高危因素。从尸检中获得组织学和微血管造影的资料,检索已发表的有关IPLs的CT和MR图像,和复习近期无症状卒中研究中提出的标准。 结果 从100份MRI扫描中发现3例IPLs
BACKGROUND & OBJECTIVE Low-density regions (hypophysoid lacunar space) [IPLs], with a single oval diameter greater than 5 mm below the outer putamen, are commonly seen on CT and MRI and are commonly reported as lacunar infarcts. To determine the clinical manifestation and pathological changes of IPLs, we evaluated the imaging, clinical manifestations, risk factors of vascular disease and histopathological features in patients with I-PLs. Methods Sequential MRI scans of IPLs were included, and patients with clinical concerns for IPLs were also included. Use a questionnaire to find out whether the patient has a high risk of vascular disease. Histological and micro-angiographic data were obtained from autopsy, published published CT and MR images of IPLs, and review of the criteria set forth in the recent asymptomatic stroke study. Results Three IPLs were found in 100 MRI scans