论文部分内容阅读
手性化合物结晶分离技术是一种从外消旋混合物中获得光学纯手性化合物的常规方法。该技术的难点在于拆分试剂和溶剂的筛选与优化组合,为了找到最优组合,往往要进行一系列耗时、枯燥而耗力的工作。Maybridge手性拆分筛选和纯化试剂盒正是为解决这一技术难点而开发的产品。它能够帮助科学家们快速找到最佳的拆分条件,以较高的收率获得高纯度的手性化合物。高性能——384种拆分试剂和溶剂组合,有助于找到最佳拆分条件快速——筛选实验可在一天内完成高效——最少仅需消耗0.4mmol外消旋混合物即可完成组合优化筛选即用——所有备选拆分试剂和溶剂均按顺序预置于96孔板中,即取即用便捷——专为快速筛选设计,阳性结果可肉眼观测或光学检测,并可轻松纯化回收手性产物
Chiral Compound Crystallization Technology is a conventional method for obtaining optically pure chiral compounds from racemic mixtures. The difficulty of this technique lies in the selection and optimization of split reagents and solvents. In order to find the optimal combination, a series of time consuming, boring and laborious tasks are often required. The Maybridge Chiral Resolution Screening and Purification Kit was developed to address this technical challenge. It helps scientists quickly find the best resolution conditions and obtain high purity chiral compounds in high yields. High performance - 384 combinations of resolving agents and solvents help to find the best resolution Fast - Screening experiments can be completed in a day Efficient - at least 0.4 mmol racemic mixture can be used to complete the combination optimization Ready to use - all ready to dispense reagents and solvents are pre-ordered in a 96-well format in a single, ready-to-use format - designed for quick screening, with positive results either macroscopically or optically and easily purified Recovered chiral product