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SD大鼠喂饲3周高脂饮食引起高脂血症，用高低2个剂量的姜黄醇提取物、血脂康和舒降之治疗，服药4周后处死动物，比较治疗前后体重变化，测定血清和肝脏的胆固醇、甘油三酯以及血糖浓度，进行疗效对比分析。实验证明三种降脂药治疗前后体重无明显差异，虽然三种降脂药均能增高血糖浓度，但尤以高剂量县黄醇提取物组和舒降之组作用显著，所有药物均能使血清甘油三酯含量降低，高剂量姜黄醇提取物组和舒降之组作用最优，所有药物均能使血清胆固醇、LDL-C含量降低，其作用高剂量县黄醇提取物组和血脂康组最佳，高剂量县黄醇提取物组亦能降低肝脏胆固醇含量，而其它各组对肝脏胆固醇和甘油三酯均无明显作用。对不同药物降血脂作用分析认为：虽然三种药均能降低血脂，但其作用姜黄醇提取物组优于舒降之和血脂康。
SD rats were fed 3-week high-fat diet to induce hyperlipidemia. They were treated with high and low doses of curcumin extract, Xuezhikang and Shujiang. Four weeks later, animals were sacrificed. Changes in body weight before and after treatment were measured. Cholesterol, triglyceride, and blood glucose concentrations in liver were compared and analyzed. Experiments showed that there was no significant difference in body weight before and after treatment of the three lipid-lowering drugs. Although all three lipid-lowering drugs can increase blood glucose concentrations, the effect of high-dose county-yellow alcohol extracts and Shujiang Decoction was significant, and all drugs could make Serum triglyceride content decreased, high-dose curcumin extract group and Shujiangzhi group had the best effect, all drugs could reduce serum cholesterol, LDL-C content, its effect of high-dose county alcohol extract group and Xuezhikang The best, high-dose, topical alcohol extracts also reduced cholesterol levels in the liver, while other groups had no significant effect on liver cholesterol and triglycerides. The hypolipidemic effect of different drugs was analyzed: Although all three drugs can reduce blood lipids, their curcuminol extract group is superior to Shujiangzhi and Xuezhikang.