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目的 :探讨ST段抬高型急性心肌梗死患者左心室功能与心肌酶峰、心电图的相关性。方法 :选择2013年2月~2015年11月到我院就诊的120例STEMI患者进行研究,经临床诊断后进行静脉药物溶栓或者经皮冠状动脉(PCI)治疗,分为早期和延迟再灌注两个组,比较两组患者的心电图、心肌酶峰、左心室功能指标。结果 :两组患者的性别、年龄、并发症及用药等均无统计学差异,但两组患者的左前降支病变血管、Killip分级及FMC有统计学差异;早期再灌注组的∑ST、∑R、∑Q、ST波、Q波、心肌酶峰指标、BNP最高值及LVEDD均显著高于延迟再灌注组,差异有统计学意义,而延迟再灌注组的LVEF略高,差异有统计学意义;早期再灌注组心电图梗死相关导联的∑ST、∑Q、ST波、Q波与Killip分级、心肌酶峰指标、BNP及LVEDD呈正相关,与LVEF呈负相关;∑R与心肌酶峰指标、BNP及LVEDD呈负相关,与LVEF呈正相关;ST段抬高幅度、Q波最大值与Killip分级、心肌酶峰指标、BNP及LVEDD呈正相关。其中BNP和LVEF与左心功能的相关性最大,差异均有统计学意义。结论 :STEMI患者心电图ST段抬高越多、Q波和心肌酶指标(CK、CK-MB、c Tn T)越高、R波越小,左心室功能越差,值的继续深入研究。
Objective: To investigate the correlation between left ventricular function and myocardial enzyme peak and electrocardiogram in patients with ST segment elevation acute myocardial infarction. Methods: A total of 120 STEMI patients who were admitted to our hospital from February 2013 to November 2015 were enrolled in the study. After clinical diagnosis, intravenous drug thrombolysis or percutaneous coronary intervention (PCI) was performed and divided into early and delayed reperfusion Two groups, compared two groups of patients ECG, myocardial enzyme peak, left ventricular function index. Results: There were no significant differences in gender, age, complications and medication between the two groups. However, there was a significant difference between the two groups in terms of vessel, Killip grade and FMC. The ΣST, Σ R, ΣQ, ST wave, Q wave, peak of myocardial enzyme peak, the highest value of BNP and LVEDD were significantly higher than delayed reperfusion group, the difference was statistically significant, while delayed reperfusion group LVEF slightly higher, the difference was statistically Significance, ΣST, ΣQ, ST wave, Q wave and Killip classification, myocardial enzyme peak index, BNP and LVEDD positive correlation of lead, ECG negative correlation with LVEF in early reperfusion group ECG; ΣR and myocardial enzyme peak BNP and LVEDD were negatively correlated with LVEF. The amplitude of ST segment elevation and Q wave maximum were positively correlated with Killip classification, peak myocardial enzyme, BNP and LVEDD. Among them, the correlation between BNP and LVEF and left ventricular function was the largest, the differences were statistically significant. CONCLUSIONS: The more ST segment elevation in STEMI patients, the higher Q wave and myocardial enzyme index (CK, CK-MB, cTn T) and the lower R wave, the worse the left ventricular function.