血管免疫母细胞性淋巴结病是近年来被认识的一种具有独特的组织学和临床特点的疾病,过去长期被误认为恶性淋巴瘤,实际上可能是由B淋巴细胞的非恶性增生所致。目前文献报道已有60例,其中多有皮肤症状。作者就所见的4例对本病的临床和组织学特点加以描述。本病患者多在50岁以上,男女发病数相等。疾病开始时很象恶性血液病,有发热、肝脾肿大、淋巴结肿大,后者可波及髂浅淋巴结和腰部主动脉区淋巴结。60%的患者有皮肤损害,表现为瘙痒、红 Angioimmunoblastic cell lymphadenopathy is a disease with unique histological and clinical features that has been recognized in recent years. It has long been mistaken for malignant lymphoma and may actually be caused by non-malignant hyperplasia of B lymphocytes. At present, 60 cases have been reported in the literature, of which many have skin symptoms. The author described the clinical and histological features of the disease in 4 cases. The patients are more than 50 years old, and the incidence of men and women are equal. At the beginning of the disease, it resembled a hematological malignancy with fever, hepatosplenomegaly, and lymphadenopathy. The latter can affect the superficial and auricular lymph nodes. 60% of patients have skin damage, manifested as itching, redness