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作者制成了一种慢性动物模型,即将 Ameroid缩窄器环置于冠状动脉上使其闭塞,以模拟运动诱发心肌缺血的临床状态。侧枝循环在休息时能维持心脏的正常功能,但运动时缺血心肌发生局部功能障碍。此模型可用于研究药物对缺血心肌收缩功能的作用。异搏停作为冠状动脉扩张剂及钙拮抗剂已
The authors made a chronic animal model of occluding the Ameroid constrictor ring on the coronary artery to mimic the clinical state of exercise-induced myocardial ischemia. Collateral circulation at rest to maintain the normal function of the heart, but during exercise ischemic myocardial dysfunction occurred locally. This model can be used to study the effects of drugs on ischemic myocardial contractile function. Verapamil as coronary dilators and calcium antagonists have been