胸膜孤立性纤维性肿瘤比较少见,长期以来一直被命名为良性间皮瘤或局限性间皮瘤,新近才认识到该肿瘤起源于胸膜间皮下未分化间叶细胞,具有纤维母细胞/肌纤维母细胞分化而非间皮来源。本文报道1例巨大胸膜孤立性纤维性肿瘤,结合文献探讨其临床病理特征、诊断和鉴别诊断。 Pleural solitary fibrous tumor is relatively rare, has long been named as benign mesothelioma or mesothelioma, has only recently realized that the tumor originated in subpleural undifferentiated mesenchymal cells, with fibroblasts / myofibrillar Differentiation of cells rather than mesothelial sources. This article reports a case of huge pleural solitary fibrous tumor, combined with the literature to explore its clinical and pathological features, diagnosis and differential diagnosis.