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33例小儿何杰金氏病(HD)发病年龄高峰为5—9岁,男女之比为4.5:1;以淋巴细胞为主型(LP型)者多为临床Ⅰ～Ⅱ期,结节硬化型(NS型)者多为Ⅱ～Ⅲ期,淋巴细胞消减型(LD型)者多为Ⅳ期,混合细胞型(MC型者)则介于Ⅰ～Ⅳ之间;LP型以累及单一浅部淋巴结为主,LD、MC及NS型常累及内脏;颈部淋巴结为最常见的发病部位。半年以内死亡率:LP型为10%,NS型为11%,MC型为14%,LD型为100%。未经治疗或经单一化疗或放疗者预后差,半年内死亡率为58%;放疗加化疗综合性治疗,预后较好,三年以上存活率为69%。
The age at onset of Hodgkin’s disease (HD) in 33 children was 5-9 years old, with a ratio of male to female of 4.5: 1. Most of the patients with lymphocyte predominance (LP type) were stage Ⅰ-Ⅱ, nodular cirrhosis Type (NS type) are mostly Ⅱ to Ⅲ, lymphocyte subtype (LD) are mostly Ⅳ, mixed cell type (MC type) is between Ⅰ ~ Ⅳ; LP type involving a single shallow Department of lymph nodes, LD, MC and NS often involving organs and internal organs; neck lymph nodes are the most common site of disease. Within six months, the mortality rate was 10% for LP type, 11% for NS type, 14% for MC type and 100% for LD type. Unextracted or chemotherapy alone or radiotherapy poor prognosis, within six months, the mortality rate was 58%; radiotherapy and chemotherapy comprehensive treatment, the prognosis is good, more than three years survival rate of 69%.