论文部分内容阅读
目的观察强化胰岛素治疗在危重病患者中的临床疗效。方法80例危重病患者随机分为两组,治疗组(40例)给予强化胰岛素治疗,使血糖维持在4.4～6.1 mmol/L;对照组(40例)给予常规胰岛素治疗,使血糖控制在10.0～11.1 mmol/L。观察两组患者使用抗生素的天数、使用呼吸机的天数、血透发生率、院内感染发生率及病死率。结果治疗组中使用抗生素天数(15±5)d,使用呼吸机天数(6±4)d,需行血透6例(15.0%),院内感染6例(15.0%),病死率17.5%,均明显低于对照组,P<0.05,差异有统计学意义。结论对于危重病患者,当出现应激性高血糖时,强化胰岛素治疗可改善危重病患者的预后,降低其病死率。
Objective To observe the clinical effect of intensive insulin therapy in critically ill patients. Methods Eighty critically ill patients were randomly divided into two groups. The treatment group (40 cases) received intensive insulin therapy and the blood glucose level was maintained at 4.4-6.1 mmol / L. The control group (40 cases) received routine insulin therapy and the blood glucose level was controlled at 10.0 ~ 11.1 mmol / L. The days of using antibiotics, days of using ventilator, incidence of hemodialysis, nosocomial infection and mortality were observed in two groups. Results The number of antibiotic days (15 ± 5) d and the number of ventilator days (6 ± 4) days in the treatment group were 6 (15.0%) with hemodialysis and 6 (15.0%) with nosocomial infection with a mortality rate of 17.5% Were significantly lower than the control group, P <0.05, the difference was statistically significant. Conclusions For critically ill patients, intensive insulin therapy can improve the prognosis and reduce the mortality of critically ill patients when stressful hyperglycemia occurs.