论文部分内容阅读
目的分析成人急性布鲁氏菌病患者的肝功能改变。方法回顾性分析125例成人急性布鲁氏菌病患者肝功能指标ALT、AST、TBil和DBil、碱性磷酸酶(ALP)、γ-谷氨酰转肽酶(γ-GT)和血清白蛋白(Alb)、球蛋白(Glb)的变化。结果治疗前后肝功能指标中ALT、AST及γ-GT、ALP的异常率差异有统计学意义(P<0.01);Alb及Glb的异常率差异有统计学意义(P<0.05);TBil异常率差异无统计学意义(P>0.05)。结论部分急性布鲁氏菌病患者肝功能指标ALT、AST及γ-GT、ALP等可有一过性异常,且以轻、中度升高为主,经过及时正规治疗后基本可以恢复正常,很少会发展成慢性肝炎。
Objective To analyze the changes of liver function in adult patients with acute brucellosis. Methods Retrospective analysis of ALT, AST, TBil and DBil, alkaline phosphatase (ALP), γ-glutamyl transpeptidase (γ-GT) and serum albumin in 125 adults with acute brucellosis (Alb), globulin (Glb) changes. Results There were significant differences in ALT, AST, γ-GT and ALP between before and after treatment (P <0.01), abnormal rates of Alb and Glb (P <0.05), abnormal rates of TBil The difference was not statistically significant (P> 0.05). Conclusions Some patients with acute brucellosis may have transient abnormalities of ALT, AST, γ-GT and ALP, which are mainly mild and moderate exacerbations. After regular treatment, they can return to normal, Less likely to develop into chronic hepatitis.