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随着促排卵药物的应用和辅助生育技术(试管婴儿)的广泛开展,及高龄孕妇的增多,近年来多胎妊娠的发生率大大增加。双胎妊娠的发生率为1%~2%,其中1/4是单绒毛膜双胎,约3/4是双绒毛膜双胎[1]。单绒毛膜双胎(Monochorionic,Mc)由一个受精卵分裂而来,根据分裂时间的不同,单卵双胎中约有70%为单绒毛膜双胎,余下30%为双绒毛膜双胎(Dichorionic,Dc)。单绒毛膜双胎并发症的发病率逐年升高,目前的一些产前治疗方法也并非最优选择,故而加强对单绒毛膜双胎妊娠及其并发症的发病原因及机制研究、尽早而准确的诊断以及因人而异的个体化治疗方案选择对改善妊娠结局、降低围产儿发病率和死亡率具有重要意义。
With the widespread use of ovulation induction drugs and assisted reproductive technology (IVF) and the increase of older pregnant women, the incidence of multiple pregnancies has greatly increased in recent years. The incidence of twin pregnancy is 1% to 2%, of which 1/4 is single chorionic twins, about 3/4 pairs of double chorionic twins [1]. Monochorionic (MC) cells are divided by a fertilized egg. About 70% of monozygotic twins are single-chorionic twins and the remaining 30% are double-chorionic twins Dichorionic, Dc). The incidence of single chorionic twin complications increased year by year, some of the current prenatal treatment is not the optimal choice, so to strengthen the single chorionic twin pregnancy and its pathogenesis and mechanism of complications, as soon as possible and accurate The diagnosis and individualized individual treatment options are important for improving pregnancy outcome and reducing perinatal morbidity and mortality.