核仁,作为细胞核的内含物,普遍存在于真核细胞中。在细胞分裂前期,核仁大约与核膜同时开始消失,在末期又重新形成。核仁是进行 rRNA 合成、核糖体颗粒组装、成熟和转运的场所。在肿瘤细胞中,核仁形态明显不同于正常细胞。核仁体积增大、数目增多、形状不规 Nucleolus, as a nuclear content, is ubiquitous in eukaryotic cells. In the early stage of cell division, the nucleolus begins to disappear at about the same time as the nuclear membrane and re-forms in the final stage. Nucleolus is a place for rRNA synthesis, ribosome particle assembly, maturation and transport. In tumor cells, nucleolus morphology is significantly different from normal cells. Nucleolus volume increased, the number increased, irregular shape