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为评价准分子激光原位角膜磨镶术（Ｌａｓｅｒｉｎｓｉｔｕｋｅｒａｔｏｍｉｌｅｕｓｉｓ，ＬＡＳＩＫ）治疗高度近视的疗效，对术前近视度为－８．００～－２５．００Ｄ的１５３眼行ＬＡＳＩＫ手术，随访１年以上。结果：术后６个月视力和屈光度基本稳定，术后１年裸眼视力≥０．５者１２７眼（占８３．０１％），其中≥１．０者６２眼（占４０．５２％）。屈光度回退３２眼（占２０．９１％），过矫５眼（占３．２７％），欠矫１９眼（占１２．４２％）。术后裸眼视力≥术前最佳矫正视力１０８眼（占７０．５９％），术后最佳矫正视力下降６眼（占３．９２％）。表明ＬＡＳＩＫ对高度近视有较好的疗效，手术安全，并发症少。但屈光回退率仍较高，ＬＡＳＩＫ手术量设计尚无专用程序，有待研究和提高。
To assess the efficacy of laser in situ keratomileusis (LASIK) for the treatment of high myopia, 153 eyes with a preoperative myopia of -8.00 to -25.00D underwent LASIK and were followed up for more than 1 year . Results: Visual acuity and refraction were basically stable at 6 months after surgery. There were 127 eyes (83.01%) with uncorrected visual acuity ≥0.5 at 1 year after operation, of which 62 eyes (40.52%) ≥1.0. Refractive degree of 32 eyes (20.91%), overcorrection in 5 eyes (3.27%), undercorrection in 19 eyes (12.42%). Postoperative uncorrected visual acuity ≥ 108 eyes preoperative best corrected visual acuity (70.59%), postoperative best corrected visual acuity decreased 6 eyes (3.92%). That LASIK has a good effect on high myopia, surgical safety, fewer complications. However, the rate of refractive regression is still high, LASIK surgery design there is no specific procedure to be studied and improved.