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目的探讨多西紫杉醇与顺铂同步化疗联合放疗治疗食管癌的疗效。方法 2005年2月至2008年2月收治的食管癌患者189例,分为同步放化疗组99例,单放疗组90例,观察两组临床疗效。结果同步放化疗组总有效率88.88%,单放疗组总有效率62.22%,两组总有效率比较P<0.05差异有统计学意义。结论多西紫杉醇与顺铂同步化疗联合放疗治疗食管癌临床效果显著,二者联合具有明显的协同作用,有疗效互补、效应相加之功效,改善患者的生活质量和延长患者生命。
Objective To investigate the efficacy of docetaxel and cisplatin combined with concurrent radiotherapy in the treatment of esophageal cancer. Methods A total of 189 patients with esophageal cancer who were treated from February 2005 to February 2008 were divided into concurrent radiochemotherapy group (n = 99) and single radiotherapy group (n = 90). The clinical curative effect was observed. Results The total effective rate was 88.88% in the concurrent chemoradiotherapy group and 62.22% in the single radiotherapy group. The total effective rate of the two groups was significantly lower than that of P <0.05. Conclusions Docetaxel combined with cisplatin and chemoradiotherapy in the treatment of esophageal cancer has a significant clinical effect. The combination of the two has obvious synergetic effect, which has the effects of complementing each other, adding the effects, improving the quality of life and prolonging the life of patients.