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自身免疫病是身体免疫失常的一类疾病,常见的有类风湿性关节炎(RA),系统红斑狼疮(Sle),多发性硬化症(MS),免疫球蛋白肾病(IgAN),Ⅰ型糖尿病。这类疾病的共同特点是:1.免疫功能失常:免疫系统对自身组织抗原失去耐受性,导致机体组织器官损伤。免疫系统在正常情况下对自身组织有耐受性,这是一种对自身抗原特异性无免疫应答状态,是正常免疫系统的基本特征,是区别自我—非自我的一种机制,这个机制失常,就会对自身组织抗原产生免疫应答反应,导致对
Autoimmune diseases are a group of diseases of immune disorders. Common diseases include rheumatoid arthritis (RA), systemic lupus erythematosus (MS), immunoglobulin nephropathy (IgAN), type I diabetes . The common features of these diseases are: 1. Immune dysfunction: Immune system loses its tolerance to their own tissue antigens, leading to organ tissue damage. The immune system is normally tolerant of its own tissue, a state of no immune response specific to the autoantigen that is a fundamental feature of the normal immune system and a mechanism that distinguishes between self-non-self, a disorder of this mechanism , It will have an immune response to their own tissue antigens, leading to right