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目的 探讨影响老年人骨密度的因素及防治老年骨质疏松的措施。方法 采用整群抽样方法对两所高等院校 2 86例 5 0岁以上老人进行骨密度及尿钙、氟、锰、镁 ,羟脯氨酸调查研究。结果 本研究表明女性骨矿物质含量和骨矿物质密度显著低于男性 (P <0 .0 1) ,女性尿钙含量明显高于男性 (P <0 .0 5 ) ,女性尿羟脯氨酸含量明显低于男性 (P <0 .0 1) ,而尿氟含量差别不明显。尿钙、锰、羟脯氨酸与骨矿物含量和骨密度呈现显著性负相关 ,尿氟与尺骨骨矿物含量和骨密度呈现显著性正相关 (P <0 .0 5或P <0 .0 1)。结论 提示尿钙、氟、锰、羟脯氨酸均可影响骨代谢。
Objective To explore the factors that affect the bone mineral density of the elderly and the measures to prevent and treat the elderly osteoporosis. Methods A cluster sampling method was used to investigate the bone mineral density, urinary calcium, fluoride, manganese, magnesium and hydroxyproline in 286 elderly people over the age of 50 in two institutions of higher learning. Results The present study showed that the bone mineral density and bone mineral density were significantly lower in females than in females (P <0.01). The urinary calcium content of females was significantly higher than that of females (P <0.05). Urinary hydroxyproline Content was significantly lower than men (P <0 01), while urinary fluoride content was not significantly different. Urine calcium, manganese, hydroxyproline and bone mineral content and bone mineral density showed a significant negative correlation, urinary fluoride and ulnar bone mineral content and bone mineral density showed a significant positive correlation (P <0.05 or P <0 .0 1). Conclusions urinary calcium, fluoride, manganese, hydroxyproline can affect bone metabolism.