作者对20例年龄为40～70岁的一组重症肌无力患者每日每公斤体重口服环孢菌素2～8mg,作为期12个月的有安慰剂对照的双盲试验。治疗6个月以后,环孢菌素治疗组与安慰剂组对比,症状明显改善。这种趋势一直持续到12个月以后。环孢菌素治疗组的乙酰胆碱受体抗体的百分率改变是较大的。本组内其乙酰胆碱受体抗体效价降低范 The authors double-blind placebo-controlled, 12-month, placebo-controlled double-blind trial of 20 to 8 mg of cyclosporine per kilogram of body weight daily in a group of 20 patients with myasthenia gravis 40 to 70 years of age. After 6 months of treatment, the symptoms were significantly improved in the cyclosporine-treated and placebo groups. This trend continues until after 12 months. The percentage change in acetylcholine receptor antibodies in the cyclosporin-treated group was greater. The group within its acetylcholine receptor antibody titers lower Fan