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应用中药、微量元素制剂配合短疗程a-干扰素、促肝细胞生长因子治疗病毒性慢性活动性肝炎并肝硬化失代偿18例(治疗组),并和19例(对照组)随机对照,疗程3个月,结果:治疗组黄疸消失者占88%(16/18),腹水消失94%(17/18);对照组分别为26%(5/19)和37%(7/19)。两组比较均P<0.01。ALT、TBil检验,治疗组均较对照组明显改善,均P<0.01,肝炎病毒复制标志物。HbsAg、HbeAg、抗-HbclgM转阴率治疗组和对照组比,均有统计学差异意义。治疗组缓解率68%(12/18),好转率28%(5/18),总有效率94%(17/18);对照组分别为16%(3/19),36%(7/19)和52%(10/19)。两组比较,缓解率、总有效率差异均有统计学意义。
Application of traditional Chinese medicine, trace elements preparations with a short course of treatment of interferon-α, hepatocyte growth factor in the treatment of viral chronic active hepatitis and cirrhosis of the decompensation in 18 cases (treatment group), and 19 cases (control group) Treatment for 3 months, the results: the treatment group disappeared jaundice accounted for 88% (16/18), ascites disappeared 94% (17/18); control group were 26% (5/19) and 37% (7/19) . The two groups were compared P <0.01. ALT, TBil test, the treatment group were significantly improved compared with the control group, all P <0.01, hepatitis virus replication markers. HbsAg, HbeAg, anti-HBcgM negative rate of treatment group and control group, there are statistically significant differences. The response rate of the treatment group was 68% (12/18), the improvement rate was 28% (5/18), the total effective rate was 94% (17/18); the control group was 16% (3/19) and 36% (7 / 19) and 52% (10/19). The two groups, the remission rate, the total effective rate differences were statistically significant.