本文分析(1983年12月31日统计资料)三苯氧胺辅助治疗早期乳癌6年多,中数随访45月的全部对照试验结果.作者共收治乳癌患者1285例,年龄≤75岁。经乳腺全切除术或乳癌根治术后,随机分组。除外不适宜本研究患者,562例服三苯氧胺(10mg,每日2次,服二年或至复发);567例为对照,不作进一步的治疗。结果:三苯氧胺组复发或死亡152例;对照组则为220例(P<1.0001)。三苯氧胺治疗失败率比对照 This article analyzes (December 31, 1983 statistical data) tamoxifen auxiliary treatment of early breast cancer more than 6 years, the median follow-up of 45 months of all controlled trials. The authors treated a total of 1285 cases of breast cancer patients, age ≤ 75 years old. After mammary gland resection or radical mastectomy, they were randomized. Excluding patients not eligible for this study, 562 patients were treated with tamoxifen (10 mg twice daily for two years or until relapse); 567 were controls and no further treatment was performed. Results: There were 152 cases of relapse or death in the tamoxifen group and 220 cases in the control group (P<1.0001). Tamoxifen treatment failure rate compared to control