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目的:观察淸胆化瘀汤联合化疗对胆囊癌的临床疗效。方法:采用随机法将40例胆囊癌患者分为治疗组(淸胆化瘀汤+化疗)20例、对照组(化疗)20例,比较两组临床完成情况、近期客观疗效、治疗前后临床症状、生活质量卡氏评分、体重、免疫功能(NK细胞)的变化和毒副反应情况。结果:治疗组较对照组可提高有效率、较好改善部分临床症状,稳定并增加体重,提高患者生存质量,保护机体免疫功能,减轻化疗毒副反应(P<0.05);但在稳定病灶方面无显著性差异(P>0.05)。结论:淸胆化瘀汤联合化疗对胆囊癌有较好的临床效果。
Objective: To observe the clinical effect of gallbladder decoction combined with chemotherapy on gallbladder cancer. Methods: Forty cases of gallbladder cancer were divided into treatment group (QDDH + chemotherapy) 20 cases and control group (chemotherapy) 20 cases by random method. The clinical outcomes, the recent objective curative effect, the clinical symptoms before and after treatment , Quality of life score, weight, immune function (NK cells) changes and toxicity. Results: The treatment group than the control group can improve the efficiency, better to improve some of the clinical symptoms, stability and increase body weight, improve patient quality of life, protect the immune function, reduce chemotherapy side effects (P <0.05); but in the stability of the lesion No significant difference (P> 0.05). Conclusion: Chijiehuayu decoction combined with chemotherapy has good clinical effect on gallbladder cancer.