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目的:提高对眼球表面鳞状细胞性肿物的诊断和治疗水平。方法:对天津眼科医院1978～1997年收治的180例眼球表面鳞状细胞性肿物进行临床和病理学分析。结果:本组病变可分为三大类:1良性病变73例(40.4%),包括鳞状细胞增生、乳头状瘤和假上皮瘤样增生;2交界性病变42例(23.3%),主要是非典型增生;3恶性病变65例(35.9%),包括原位癌、鳞状细胞癌和粘液表皮样癌。本组病变好发于角膜缘部位(118例),男性多见(145例),通常为单眼发病,多数发病时间为半年～1年内。手术后复发主要与肿物切除不彻底有关。结论:对眼球表面鳞状细胞性肿物的术前正确诊断、手术设计和手术边缘的病理学检查是非常重要。
Objective: To improve the diagnosis and treatment of squamous cell mass on the surface of the eyeball. Methods: The clinical and pathological features of 180 cases of ocular surface squamous cell carcinoma in Tianjin Eye Hospital from 1978 to 1997 were analyzed. Results: The group of lesions can be divided into three categories: 1 benign lesions in 73 cases (40.4%), including squamous cell hyperplasia, papilloma and pseudopothelioma-like hyperplasia; 2 borderline lesions in 42 cases (23.3%), mainly Is atypical hyperplasia; 3 malignant lesions in 65 cases (35.9%), including carcinoma in situ, squamous cell carcinoma and mucoepidermoid carcinoma. This group of lesions occur in the limbus (118 cases), more common in men (145 cases), usually monocular disease, most of the onset time of six months to 1 year. The main recurrence after surgery and tumor resection is not complete. CONCLUSIONS: Correct preoperative diagnosis of the squamous cell mass on the surface of the eye, surgical design, and pathologic examination of the surgical margin are important.