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目的探讨抗氧化剂硫辛酸对糖尿病周围神经病变的疗效和安全性。方法对本院收治的108例糖尿病周围神经病变的患者随机分为观察组和对照组,观察组的患者给予抗氧化剂硫辛酸治疗,对照组患者给予前列地尔和甲钴胺治疗。结果经过治疗,对照组临床疗效的总有效率为68.18﹪,观察组患者治疗疗效的总有效率为90.63%,两组患者在临床疗效上的差异具有统计学意义(P<0.05),具有临床价值。结论抗氧化剂硫辛酸对糖尿病周围神经病变取得的临床疗效显著,是一种安全有效地临床治疗方法。
Objective To investigate the efficacy and safety of antioxidant lipoic acid in diabetic peripheral neuropathy. Methods A total of 108 patients with diabetic peripheral neuropathy admitted to our hospital were randomly divided into observation group and control group. Patients in observation group were treated with lipoic acid, and those in control group were treated with alprostadil and mecobalamin. Results After treatment, the total effective rate was 68.18% in the control group and 90.63% in the observation group. There was a statistically significant difference in clinical efficacy between the two groups (P <0.05) value. Conclusions Antioxidant lipoic acid has a significant clinical effect on diabetic peripheral neuropathy and is a safe and effective clinical treatment.