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家族性肝细胞癌少见,但也有少数报告。不论是家族性还是散发的肝细胞癌与HBsAg之间均有明显联系。有迹象证明母亲可播传HBsAg。作者报告一家两代中,4人死于肝细胞癌。其生存者中又有HBsAg高患率。这提示母亲传播HBsHg和对肝细胞癌的易感性。病例系新西兰一家庭中,于1976年底至1979年末,66岁的母亲及其33~46岁的3个儿子,其中HBsAg阳性二人。其母与其第二个丈夫的10个尚存活的孩子中(一个为同母异父同胞),有9人HBsAg阳性,而当地健康献血员,HBsAg阳性率仅为6.7%。在新西兰肝细胞癌罕见,毛利人的发病率为4/10
Familial hepatocellular carcinoma is rare, but there are also a few reports. Whether familial or distribution of hepatocellular carcinoma and HBsAg were significantly linked. There are signs that mothers can broadcast HBsAg. The authors report that one in two generations died of hepatocellular carcinoma in four people. The survivors have a high prevalence of HBsAg. This prompts the mother to spread HBsHg and its susceptibility to hepatocellular carcinoma. Case A New Zealand family, from the end of 1976 to the end of 1979, a 66-year-old mother and her 33-46-year-old three sons, including HBsAg-positive two. Nine of them were HBsAg positive from their mother and 10 surviving children from her second husband (one from her own country), compared to 6.7% for local healthy blood donors. In New Zealand rare hepatocellular carcinoma, Maori incidence rate of 4/10