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用酶联免疫吸附法(ELISA)和比色分析法测定了20名正常人血浆组织型纤溶酶原激活剂(Tissue plasminogen activator,tPA)的含量、活性及纤溶酶原激活剂抑制物(Plasminogen activator inhibitor,PAI)的活性。检测到正常人在静脉血流阻断后,血浆tPA含量、活性均有显著增高,PAI活性变化不大。讨论了血浆tPA和PAI测定的临床意义。
Tissue plasminogen activator (tPA) levels and activities of 20 healthy individuals were measured by enzyme-linked immunosorbent assay (ELISA) and colorimetric assay. The levels of plasminogen activator inhibitor ( Plasminogen activator inhibitor, PAI) activity. The detection of normal blood flow in the venous block, plasma tPA levels, activity were significantly increased, little change in PAI activity. The clinical significance of plasma tPA and PAI measurements was discussed.