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目的探讨宫颈上皮内瘤变的临床特征及应用LEEP治疗的手术效果。方法对2009年1月至2011年9月收治的CIN患者108例,均经阴道镜下活检病理证实。所有患者行LEEP术,观察术后临床效果。结果所有患者均顺利完成手术,未诉明显不适,少数出现下腹坠痛,坠胀烧灼感均能忍受。手术时间5～10min,术中出血量5～50ml,平均8.0ml。根据病变范围,切除宽度平均2cm,切除深度1.5cm。LEEP治疗CIN治愈率为92.59%(100/108),病变残留率为7.41%(8/108),1例随访3个月后复发1例,行2次锥切后治愈。结论 LEEP术是诊治CIN安全有效的方法,术后并发症少,治愈率高,且病变残留复发率低,值得临床推广应用。
Objective To investigate the clinical characteristics of cervical intraepithelial neoplasia and the effect of LEEP treatment. Methods From January 2009 to September 2011, 108 patients with CIN were examined by colposcopic biopsy. All patients underwent LEEP surgery to observe the clinical effect. Results All patients were successfully completed the operation, did not complain obvious discomfort, a small number of lower abdomen fall pain, bulging burning sensation can endure. Surgery time 5 ~ 10min, intraoperative blood loss 5 ~ 50ml, an average of 8.0ml. According to the extent of the lesion, the average removal width of 2cm, resection depth of 1.5cm. LEEP treatment of CIN cure rate was 92.59% (100/108), the residual disease rate was 7.41% (8/108), 1 case of 3 months after the recurrence in 1 case, 2 times after conization. Conclusion LEEP is a safe and effective method for the diagnosis and treatment of CIN. There are few postoperative complications, high cure rate and low residual disease recurrence rate, which is worthy of clinical application.