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目的观察注射用盐酸川芎嗪治疗急性脑梗死疗效。方法将100例脑梗死患者随机分为两组,治疗组50例,对照组50例。治疗组给予常规治疗加注射用盐酸川芎嗪静脉点滴治疗;对照组给予常规治疗加复方丹参注射液治疗。全部患者于治疗14d后,评估其临床疗效,另外于治疗前和治疗14d后测定各项指标如血液流变学、血纤维蛋白原、血生化、血脂等。结果治疗组治疗前后及两组治疗后血液流变学参数和神经功能缺损评分均有非常明显改善(P<0.01)。结论注射用盐酸川芎嗪治疗脑梗死疗效明显优于对照组。
Objective To observe the curative effect of tetramethylpyrazine hydrochloride for injection on acute cerebral infarction. Methods 100 cases of cerebral infarction were randomly divided into two groups, 50 cases in the treatment group and 50 cases in the control group. The treatment group was given routine treatment plus injection of tetramethylpyrazine hydrochloride intravenously; the control group given conventional treatment plus compound Salvia injection. All patients were evaluated for their clinical efficacy after 14 days of treatment, and other indexes such as hemorheology, fibrinogen, blood biochemistry, blood lipids, etc. were measured before treatment and after 14 days of treatment. Results The hemorrheological parameters and neurological deficit scores of the treatment group before and after treatment and both groups were significantly improved (P <0.01). Conclusion The injection of tetramethylpyrazine hydrochloride is superior to the control group in the treatment of cerebral infarction.