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目的对手术患者抗菌药物合理性情况进行分析,促进临床合理用药。方法随机抽取南阳市中心医院2008年、2009年每个季度出院手术病历各15份,共120份,依据相关管理规定,对抗菌药物使用合理性进行评价。结果抗菌药物使用率为100%,主要为第二代头孢菌素类(15.1%)、第三代头孢菌素类(20.8%)、头霉素类(24.5%)等,不合理现象主要存在于适应证(18.3%)、药物选择(68.4%)、单次剂量(43.9%)、术前用药时间(58.2%)和术后用药(86.7%)等项目中。结论手术患者预防性应用抗菌药物仍存在不合理现象,应加强管理,促进抗菌药物合理应用。
Objective To analyze the rationality of antibacterials in surgical patients to promote clinical rational use of drugs. Methods Nanyang Central Hospital randomly selected 15 medical records of discharged surgical patients in each quarter of 2008 and 2009 respectively. A total of 120 medical records were used to evaluate the rational use of antimicrobial drugs according to the relevant administrative regulations. Results The antibacterials utilization rate was 100%, mainly including the second generation cephalosporins (15.1%), the third generation cephalosporins (20.8%) and the cephamycins (24.5%). The unreasonable phenomenon mainly existed Among the indications (18.3%), drug choice (68.4%), single dose (43.9%), preoperative medication time (58.2%) and postoperative medication (86.7%). Conclusion There is still an irrational use of prophylactic antibiotics in surgical patients. Management should be strengthened to promote the rational use of antibiotics.