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目的:观察奥美拉唑对我国老年人反流性食管炎的疗效。方法:老年人反流性食管炎45例,男性41例,女性4例,年龄75±s5a,单以奥美拉唑20mg,po,qd,治疗8wk。结果:治疗8wk临床全部有效,内镜检查的愈合率93%,愈合者停药2mo,6mo,12mo累积复发率分别为60%,82%,91%;39例复发者15例需20mg,qd,19例需2d服20mg,5例需3d服20mg维持治疗,观察3~12mo,症状缓解率分别为100%,89%,60%。结论:奥美拉唑对我国老年人反流性食管炎的近期及维持治疗均有良好疗效,但停药后复发率高,需维持治疗,且维持剂量不宜过低
Objective: To observe the curative effect of omeprazole on reflux esophagitis in our country. Methods: 45 elderly reflux esophagitis, 41 males and 4 females, age 75 ± s5a, single omeprazole 20mg, po, qd, treatment 8wk. Results: The treatment of 8wk clinical all effective endoscopic healing rate of 93%, the healing time 2mo, 6mo, 12mo cumulative recurrence rates were 60%, 82%, 91%; 39 cases of recurrence in 15 cases required 20mg, qd , 19 cases required 2d serving 20mg, 5 cases required 3d serving 20mg maintenance treatment, observation of 3 ~ 12mo, symptom relief rates were 100%, 89%, 60%. Conclusion: Omeprazole has a good curative effect on the short-term and sustained treatment of reflux esophagitis in our country. However, the relapse rate after omeprazole withdrawal is high, so the treatment should be maintained and the dosage should not be too low