目的：观察奥美拉唑对我国老年人反流性食管炎的疗效。方法：老年人反流性食管炎４５例，男性４１例，女性４例，年龄７５±ｓ５ａ，单以奥美拉唑２０ｍｇ，ｐｏ，ｑｄ，治疗８ｗｋ。结果：治疗８ｗｋ临床全部有效，内镜检查的愈合率９３％，愈合者停药２ｍｏ，６ｍｏ，１２ｍｏ累积复发率分别为６０％，８２％，９１％；３９例复发者１５例需２０ｍｇ，ｑｄ，１９例需２ｄ服２０ｍｇ，５例需３ｄ服２０ｍｇ维持治疗，观察３～１２ｍｏ，症状缓解率分别为１００％，８９％，６０％。结论：奥美拉唑对我国老年人反流性食管炎的近期及维持治疗均有良好疗效，但停药后复发率高，需维持治疗，且维持剂量不宜过低 Objective: To observe the curative effect of omeprazole on reflux esophagitis in our country. Methods: 45 elderly reflux esophagitis, 41 males and 4 females, age 75 ± s5a, single omeprazole 20mg, po, qd, treatment 8wk. Results: The treatment of 8wk clinical all effective endoscopic healing rate of 93%, the healing time 2mo, 6mo, 12mo cumulative recurrence rates were 60%, 82%, 91%; 39 cases of recurrence in 15 cases required 20mg, qd , 19 cases required 2d serving 20mg, 5 cases required 3d serving 20mg maintenance treatment, observation of 3 ~ 12mo, symptom relief rates were 100%, 89%, 60%. Conclusion: Omeprazole has a good curative effect on the short-term and sustained treatment of reflux esophagitis in our country. However, the relapse rate after omeprazole withdrawal is high, so the treatment should be maintained and the dosage should not be too low