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应用免疫组织化学方法研究了２９例不同胎龄水囊引产胎儿和１例新生儿垂体前叶Ｐ物质（ＳＰ）免疫反应神经纤维的形态及分布。胎儿及新生儿垂体前叶中ＳＰ反应纤维粗细不等，有大小不一的膨体；部分纤维丛状曲屈盘绕分布，部分为稀疏的弥散走行。纤维主要位于前叶中央区及其与外侧区的交界部位，与血管及腺组织均有接触。在３～５月龄垂体前叶内ＳＰ纤维较少，纤维短而粗，膨体少且小，纤维丛较小和稀疏；６～１０月龄ＳＰ纤维增多、增长，其上膨体增多，纤维丛增大增密。结果表明，胎儿垂体前叶存在ＳＰ免疫阳性纤维，形态及分布随发育而变化。
Immunohistochemistry was used to study the morphology and distribution of substance P (SP) immunoreactive nerve fibers in 29 fetuses of different gestational age and newborn infants. Fibers and neonates in the anterior pituitary SP response fibers ranging in thickness, with different sizes of bulge; part of the fiber plexiform kyphosis around the distribution, part of the sparse dispersion walking. Fibers are mainly located in the central area of the anterior leaf and the border area with the lateral area, with the vascular and glandular tissues are in contact. In the 3 to 5 months old anterior pituitary, there were less SP fibers, shorter and thicker fibers, smaller and smaller bulges, smaller and thinner fiber bundles; SP fibers increased and grew 6 to 10 months old, Fiber thickening increases encryption. The results showed that there was SP positive immunofluorescence in the anterior pituitary of fetus, and its morphology and distribution varied with development.