有研究认为骨坏死是由于持续的血栓和(或)纤溶活性降低阻塞颌骨血液回流的髓内静脉和血窦,加重髓内压力,导致缺氧和骨细胞死亡,而产生以慢性、持续不断疼痛为特征的洞腔性骨坏死诱导的神经痛,作者对其治疗研究如下。 研究对象为124例有严重面部疼痛且活检为牙槽骨洞腔性骨坏死的患者,其中仅27％的患者凝血指标正常。纤溶活性降低和成血栓趋向均有异常的生化和免疫检测结果。其中26例(4例男性,22例女性)经过 Some studies suggest that osteonecrosis is due to persistent thrombosis and / or reduced fibrinolytic activity to block the intramedullary venous blood and sinusoids that block the return of jaw blood, aggravating intramedullary pressure, leading to hypoxia and osteocyte death, resulting in chronic, sustained Continuous pain characterized by intracavitary osteonecrosis-induced neuralgia, the authors of its treatment are as follows. The study consisted of 124 patients with severe facial pain who were biopsied for osteonecrosis of the alveolar bone, of whom only 27% had normal clotting parameters. Fibrinolytic activity and thrombotic trends have abnormal biochemical and immunoassay results. Of these, 26 (4 males and 22 females) passed