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检查167例SLE患者。结果表明:基底细胞液化变性及表皮棘层萎缩与SLE患者血沉,血清抗DS-DNA抗体结合率、血清总补体及C_3补体、冷球蛋白、尿蛋白及临床活动性有统计学意义的相关性;表皮细胞内水肿与上述大部分免疫学指标及临床活动性均有统计学意义的相关性;角化过复及胶原纤维嗜伊红染色增强与上述所有免疫学指标及临床活动性均无相关性;上述五种皮肤病理变化与SLE患者血清抗核抗体(ANA)及lgG,均无统计学意义的相关性。
167 patients with SLE were examined. The results showed that the basal cell liquefaction degeneration and epidermal spondylolisthesis and SLE patients with erythrocyte sedimentation rate, serum anti-DS-DNA antibody binding rate, serum total complement and C_3 complement, cryoglobulins, urinary protein and clinical activity was statistically significant correlation ; Epidermal intracellular edema and most of the above immunological indicators and clinical activity were statistically significant correlation; hyperkeratosis and collagen fiber eosin staining enhanced with all the above immunological indicators and clinical activity were not related ; The above five pathological changes in patients with SLE serum anti-nuclear antibody (ANA) and lgG, no statistically significant correlation.