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男性患者,48岁。因全身皮肤发红伴脱屑25天入院。一月前因双下肢出现成群疱疹伴奇痒,口服氨苯砜100mg一日三次,五天后全身皮肤潮红,大片脱屑,伴高热(达40℃),某医院给予青、链霉素,强地松治疗,同时静滴氢考,治疗25天症状未能缓解,且出现满月脸转来我院。查体温38.5℃,血压146/82mmHg,急性病容,神智清楚,满月脸,全身皮肤潮红、干燥、脱屑呈落叶状,左腋及双侧腹股沟区淋巴结如花生米大小,有压痛,巩膜不黄,左肩胛区可闻湿性罗音。胸片示左下间质性肺炎。肝功能;SGPT 183~u, 1.112~u,T.T.T[+],T.F.T[+]。肾功能:NPN42mg％,Cr 1.6mg％, BuN 16.5mg％。ECG窦性心律心肌损害。入院后诊为由氨苯砜引起的剥脱性皮炎。除停用
Male patient, 48 years old. Due to systemic redness with scaling 25 days admission. A group of herpes zoster patients with odd itch appeared a month ago, dapsone 100mg three times a day, five days after the whole body flushing, large desquamation, with high fever (up to 40 ℃), a hospital to give green, streptomycin, Prednisone treatment, while intravenous hydrogen test, the symptoms of treatment for 25 days failed to alleviate, and the full moon face turned to our hospital. Check body temperature 38.5 ℃, blood pressure 146/82 mmHg, acute disease, clear mind, full moon face, systemic skin flushing, dry, desquamation was deciduous, left axillary and bilateral inguinal lymph nodes such as peanuts size, tenderness, sclera not yellow , Left shoulder blade area can smell wet rales. Chest X-ray showed lower left interstitial pneumonia. Liver function; SGPT 183 ~ u, 1.112 ~ u, T.T.T [+], T.F.T [+]. Renal function: NPN 42 mg%, Cr 1.6 mg%, BuN 16.5 mg%. ECG sinus rhythm myocardial damage. After admission, dapsone dermatitis caused by dapsone was diagnosed. Disable