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目的观察氩氦刀治疗非小细胞肺癌的近期疗效及患者的生存质量。方法非小细胞肺癌行氩氦刀冷冻消融加化疗32例,单纯化疗36例,2组化疗方案均为顺铂加紫杉醇。比较2组一年期的临床疗效、生命质量评分。结果冷冻消融组有效率(CR+PR)75%,优于化疗组44.4%(P<0.05);2组Ⅱ、Ⅲ期生命质量评分差异有统计学意义(P<0.05)。结论晚期非小细胞肺癌的氩氦刀冷冻治疗近期效果显著,能显著改善患者生存质量。
Objective To observe the short-term curative effect and quality of life of patients treated with argon-helium knife in non-small cell lung cancer. Methods 32 cases of non-small cell lung cancer were treated with argon-helium cryosurgery and chemotherapy, 36 cases were treated with chemotherapy alone. The two chemotherapy regimens were cisplatin plus paclitaxel. One-year clinical efficacy and quality of life scores were compared between the two groups. Results The effective rate of cryoablation was 75% (CR + PR), which was better than that of chemotherapy group 44.4% (P <0.05). The difference of quality of life between two groups was statistically significant (P <0.05). Conclusion The cryosurgical cryoablation of advanced non-small cell lung cancer has a significant short-term effect and can significantly improve the quality of life of patients.