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目的 :观察后程加速超分割放疗加化疗治疗食管鳞癌的近期疗效。方法 :2 4例行后程加速超分割放疗的患者 ,分别于放射治疗的第 1、4周给予CF +DDP + 5 Fu化疗 ,5d为一个疗程 ,共 2个疗程。放疗结束时评定疗效。结果 :完全缓解率为 37.5 % ( 9/ 2 4 ) ,部分缓解率为 5 4 .2 % ( 13/ 2 4 ) ,总缓解率为 91.6 %。毒副反应的发生率较高。结论 :后程加速超分割放疗加化疗治疗食管鳞癌的近期疗效较好 ,虽毒副反应增加 ,但患者可以耐受
Objective: To observe the short-term effect of late-course accelerated hyperfraction radiotherapy and chemotherapy for esophageal squamous cell carcinoma. Methods: Twenty-four patients undergoing accelerated hyperfractionated radiotherapy were given CF + DDP + 5 Fu chemotherapy at week 1 and week 4 of radiotherapy, respectively, for 5 days for 2 courses. Assessment of efficacy at the end of radiotherapy. Results: The complete remission rate was 37.5% (9/2 4). The partial remission rate was 54.2% (13/2 4). The overall remission rate was 91.6%. The incidence of toxic reactions is high. Conclusions: Late course accelerated hyperfractionation plus chemotherapy for esophageal squamous cell carcinoma has a good short-term curative effect. Although the side effects are increased, patients can tolerate