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目的:分析维吾尔族原发性高血压伴肥胖患者血脂及血尿酸水平。方法:选择维吾尔族原发性高血压患者124例及维吾尔族非高血压患者116例为研究对象。根据体重指数≥28g/m2为肥胖,病人被分为高血压伴肥胖组(64例)、高血压无肥胖组(60例)和肥胖无高血压组(57例)、无高血压无肥胖组(59例),分别测定血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)、载脂蛋白(Apo)-AI、APO-B、血尿酸(UA)浓度。结果:①高血压伴肥胖组血TC、TG、LDL-C、UA浓度较高血压无肥胖组及无高血压无肥胖组显著升高(P<0.05);②高血压伴肥胖组血脂、UA浓度与肥胖无高血压组相比无显著差异(P>0.05);③高血压无肥胖组TC、LDL-C水平较无高血压无肥胖组显著升高(P<0.05);④肥胖无高血压组TC、TG、LDL-C、UA水平较无高血压无肥胖组显著升高(P<0.05)。结论:维吾尔族原发性高血压伴肥胖患者存在血脂和血尿酸水平升高等代谢紊乱的倾向。
Objective: To analyze the levels of serum lipids and serum uric acid in Uygur patients with essential hypertension and obesity. Methods: 124 Uygur patients with essential hypertension and 116 Uyghur non-hypertensive patients were selected as the study subjects. According to the body mass index ≥28g / m2 as obesity, the patients were divided into obesity group (64 cases), obesity group (60 cases) and obesity without hypertension group (57 cases), without obesity group (59 cases). The levels of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), apolipoprotein ) -AI, APO-B, uric acid (UA) concentrations. Results: ①The levels of TC, TG, LDL-C and UA in hypertensive obesity group were significantly higher than those in non-obese hypertensive group and non-obese hypertensive group (P <0.05); ② The levels of serum lipids, UA (P> 0.05). ③The levels of TC and LDL-C in hypertensive no obesity group were significantly higher than those in non-obese hypertensive group (P <0.05) Blood pressure group TC, TG, LDL-C, UA levels were significantly higher than those without hypertension without obesity (P <0.05). Conclusion: There is a tendency of metabolic disorders such as elevated serum lipids and uric acid in Uighur patients with essential hypertension and obesity.