在电子显微镜应用的初期,由于没有找到一种适用于生物标本的包埋介质,不能切得薄片,所以关于生物材料超微结构的研究工作取得的进展不大。1949年Newman等人提出用甲基丙烯酸酯作为生物材料的包埋介质,但随后的实践表明,甲基丙烯酸酯对细微结 In the early stage of electron microscopy, there was not much progress in the research on the ultrastructure of biomaterials because no embedding media suitable for biological specimens could be found and no slices could be cut. In 1949, Newman et al. Proposed the use of methacrylate as a biomaterial embedding medium, but subsequent practice showed that the effect of methacrylate on the fine junction