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目的观察中医辨证论治结合高强度聚焦超声(HIFU)治疗原发性肝癌的疗效。方法中医辨证论治结合HIFU治疗原发性肝癌25例,中医辨证分型分为肝热血瘀、肝盛脾虚、肝肾阴亏三型,配合HIFU治疗,观察临床症状、近期疗效、甲胎蛋白(AFP)及不良反应。结果治疗后主要临床症状肝区痛、发热、腹胀、纳呆、乏力的缓解率分别为76.2%、66.7%、70.6%、80.0%、58.8%;治疗总有效率为52.0%,稳定率为84.0%;23例患者的AFP出现下降,其中2例降至正常范围,2例出现轻度升高;25例患者均未出现严重不良反应,部分患者出现轻至中度不良反应。结论中医辨证论治结合HIFU治疗原发性肝癌具有明显缓解症状、降低AFP、控制肿瘤的作用,而且不良反应较小。
Objective To observe the therapeutic effect of syndrome differentiation of traditional Chinese medicine (TCM) combined with high intensity focused ultrasound (HIFU) on primary liver cancer. Methods TCM syndrome differentiation combined with HIFU treatment of 25 cases of primary hepatocellular carcinoma, TCM syndrome differentiation is divided into three types of liver heat and blood stasis, liver and spleen, liver and kidney type, with HIFU treatment, clinical symptoms, short-term efficacy, AFP ) And adverse reactions. Results After treatment, the main clinical symptoms of liver pain, fever, bloating, poor appetite and remission rates were 76.2%, 66.7%, 70.6%, 80.0%, 58.8%; the total effective rate was 52.0%, the stability rate was 84.0 %; AFP in 23 patients decreased, 2 of them fell to the normal range, 2 patients showed mild increase; 25 patients did not appear serious adverse reactions, some patients with mild to moderate adverse reactions. Conclusion TCM syndrome differentiation combined with HIFU treatment of primary hepatocellular carcinoma has obvious relieve symptoms, reduce AFP, the role of tumor control, and the adverse reaction is small.