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Ｇｒａｖｅｓ病 (ＧＤ)和桥本甲状腺炎 (ＨＴ)是常见的器官特异性自身免疫性疾病 ,其发病是遗传易感基因和环境因素共同作用的结果。本研究采用国家标准化尿碘测定方法测定山东沿海地区不同人群的尿碘 ,将碘营养状况和易感ＨＬＡ等位基因等因素结合起来分析 ,观察它们对ＧＤ、
Graves disease (GD) and Hashimoto’s thyroiditis (HT) are common organ-specific autoimmune diseases, the onset of which is the result of a combination of genetic susceptibility genes and environmental factors. In this study, we measured the urinary iodine of different populations in the coastal areas of Shandong by the method of national standardized urinary iodine determination, combined the iodine nutrition status and the susceptible HLA alleles, and observed their effects on GD,