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目的:探讨安徽省安庆市新型冠状病毒肺炎（coronavirus disease 2019，COVID-19，简称新冠肺炎）患者的流行病学及临床特征。方法:采用回顾性研究方法，纳入2020年1月23日—2020年2月11日在安庆市三甲医院确诊的80例COVID-19患者，对其流行病学及临床资料进行收集。结果:80例确诊患者分布于安庆各地区，其中有武汉暴露史者47例（58.8%），密切接触新冠肺炎患者引起发病者29例（36.2%），暴露史不明确者4例（5.0%）。确诊患者中男女性别比为3:2，平均年龄42.2岁，职业以工人/农民为主（42.5%）。80例确诊患者有8例（10.0%）在就诊时无任何症状，其余72例（90.0%）患者从发病到就诊中位时间为5.0 d。临床症状主要包括：发热62例（77.5%）、干咳34例（42.5%）、乏力29例（36.3%）等。实验室检查结果一般表现为白细胞降低17例（21.3%）、淋巴细胞降低34例（42.5%）、活化部分凝血活酶时间（activated partial thromboplastin time，APTT）时间延长46例（57.5%）、C反应蛋水平升高49例（61.3%）,个别患者存在肝肾功能损害。多数患者的CT影像学改变以磨玻璃样阴影（60.0%）和斑片状阴影（25.0%）为主，累及双肺患者（68.8%）多于单肺患者（21.3%）。治疗以α-干扰素雾化吸入、洛匹那韦/利托那韦、中药制剂等为主，80例患者均预后良好。结论:COVID-19传染性强，隐匿性强，应对重点人群强化管理及自我防护，对密切接触者早发现、早隔离、早诊断、早治疗。“,”Objective:To analyze the epidemiological characteristics and clinical features of coronavirus disease 2019 (COVID-19) cases in Anqing city of Anhui province.Methods:The epidemiological and clinical data of 80 COVID-19 patients diagnosed in a tertiary hospital of Anqing area from the January 23 to February 11, 2020 were collected, and the data were analyzed with a retrospective study.Results:The 80 patients distributed in each county of Anqing city, including 47 cases (58.8%) with exposure history related to Wuhan, 29 close contacts (36.2%) of COVID-19 patients and 4 cases (5.0%) with unidentified contact history. Among the confirmed cases, the male-to-female ratio was 3:2 and the average age was 42.2 years old. The occupations of the patients were mainly workers/peasants (42.5%). Among the 80 confirmed cases, 8 patients (10.0%) had no symptoms when they were in the hospital, and the median time from onset to diagnosis for the other 72 patients (90%) was 5.0 days. The main clinical symptoms were fever in 62 cases (77.5%), dry cough in 34 cases (42.5%), and fatigue in 29 cases (36.3%) The routine blood test showed decreased white blood cell counts in 17 cases (21.3%), decreased lymphocyte counts in 34 cases (42.5%), increased activated partial thromboplastin time (APTT) in 34 cases (57.5%) and increased level of C-reaction protein (CRP) in 49 cases (61.3%). Some patients had mild liver and kidney damage. Most patients showed ground glass shadow (60.0%) and patchy ground glass shadow (25.0%) in CT. Patients with both lung affected (68.8%) were more common than patients with single lung afftected (21.3%). All 80 COVID-19 patients showed good prognosis after treatments with interferon-α inhalation, lopinavir/ritonavir and Traditional Chinese Medicine.Conclusions:COVID-19 was highly infectious with strong concealment. Management and self-protection for high-risk population should be enforced. Early detection, early isolation, early diagnosis and early treatment should be applied to close contacts.