白癜风是一种获得性色素脱失性皮肤病,本病易诊难治,可对大部分患者心理方面带来许多负面影响,从而降低患者的生活质量.其发病机制相对复杂,大多数学者认为与遗传、免疫及神经因素有关.而最近研究发现维生素D可以改善白癜风疾病的发生与发展,这可能与维生素D在免疫和神经系统中起着关键的作用有关.本文现对维生素D与白癜风之间的关系做一综述,希望对白癜风的临床治疗提供参考.“,”Vitiligo is a common acquired depigmentation of skin disease, which is easy to be diagnosed but hard to be completely cured. The vitiligo not only brings numerous negative effects on the mentality of patients, but also significantly impairs the quality of their life. While the real problem is that vitiligo has a complex pathogenesis. In most cases, researchers believe that the development of vitiligo is associated with genetic, immunological and neurological factors. However, recent reports indicated that vitamin D could ameliorate the progression of vitiligo.It may because of that vitamin D play a key role in the both immune and nervous system. The present review highlights the relationship between vitamin D and vitiligo, so as to provide references for the treatment of vitiligo.